Author

Daniel Fochtman

Institute of Bioorganic Chemistry, Polish Academy of SciencesORCID 0000-0002-0754-7012Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Marta GawiniD· 2 shared Monika PietrowskaiD· 2 shared Agnieszka BędzińskaiD· 1 shared Aldo Leal‐EgañaiD· 1 shared Ananya ChoudhuryiD· 1 shared Andrea Petzold· 1 shared Aneta ZebrowskaiD· 1 shared Angelika BorkowetziD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

Marta GawinORCID

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2 papers

Recent·Most cited

Blood-based detection of MMP11 as a marker of prostate cancer progression regulated by the ALDH1A1-TGF-β1 signaling mechanism

Ielizaveta Gorodetska, Vasyl Lukiyanchuk, Marta Gawin, Myroslava Y. Sliusar, Annett Linge, Fabian Lohaus, Tobias Hölscher, Kati Erdmann, Susanne Fuessel, Angelika Borkowetz, Anna Wojakowska, Daniel Fochtman, Mark Reardon, Ananya Choudhury, Yasmin Antonelli, , Anna Dubrovska

This study identifies MMP11 as a blood-based biomarker for prostate cancer progression, regulated by the ALDH1A1-TGF-β1 signaling pathway.

Journal of Experimental & Clinical Cancer Research · Mar 23, 2025Peer-reviewedCancer Biology

Serpins A1/A3 within tumor-derived extracellular vesicles support pro-tumoral bias of neutrophils in cancer

Maksim Domnich, Ekaterina Pylaeva, Elena Siakaeva, Nastassia Kabankova, Agnieszka Będzińska, Damian Robert Sojka, Aneta Zebrowska, Marta Gawin, Maren Soldierer, Malwina Rist, Daniel Fochtman, Irem Ozel, Bernd Giebel, Iris Helfrich, Ilona Thiel, , Jadwiga Jabłońska

This study shows tumor-derived extracellular vesicles containing serpins A1/A3 reprogram neutrophils to support tumor growth by extending their lifespan and suppressing CD8 T cells.

bioRxiv · Mar 6, 2025 · PreprintCancer Biology