Author

Laura Raggi

The San Raffaele Telethon Institute for Gene TherapyORCID 0000-0003-0809-9909Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1 Assay:protein structure· 1

Frequent Co-Authors

Alberto BoldriniiD· 1 shared Alessandra BalduiniiD· 1 shared Alessandro GalbiatiiD· 1 shared Alessandro GulinoiD· 1 shared Alessandro MalaraiD· 1 shared Alexandros PatsilinakosiD· 1 shared Andrea AstolfiiD· 1 shared Annamaria AprileiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

Alberto BoldriniORCID

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2 papers

Recent·Most cited

Protein Folding Interference Enables Selective Cyclin D1 Degradation

Alessandro Galbiati, Enrica Colasurdo, Alexandros Patsilinakos, Simone Lanfredini, Serena Bonifati, Tania Massignan, Carmine Varricchio, Leda Bencheva, Alberto Boldrini, Luca Terruzzi, Gianluca Papeo, Andrea Astolfi, Laura Raggi, Marta Pandini, Giulia Frapporti, , Giovanni Spagnolli

This paper identifies a folding intermediate of Cyclin D1 as a target for selective degradation, showing that pharmacological interference with this state inhibits tumor growth and overcomes resistance to CDK4/6 inhibitors.

bioRxiv · Oct 25, 2026 · PreprintBiochemistry

A genetic anemia disentangles the dual effect of chronically reduced thrombopoietin on hematopoietic stem cells and bone marrow niche

Annamaria Aprile, Alessandro Malara, Mariangela Storto, Alessandro Gulino, Valeria Cancila, Gaia Morello, Silvia Sighinolfi, Laura Raggi, Stefano Beretta, Ivan Merelli, Sarah Marktel, Maurilio Ponzoni, Claudio Tripodo, Alessandra Balduini, Giuliana Ferrari

This study uses a genetic anemia model to show that reduced thrombopoietin affects hematopoietic stem cells and the bone marrow niche through direct and indirect mechanisms.

bioRxiv · Oct 9, 2026 · PreprintCell Biology