Author

Tomáš Drmota

ORCID 0000-0002-3422-127XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 1

Frequent Co-Authors

Anna SzlachciciD· 2 shared Daria Gajewska· 2 shared Janusz WiśniewskiiD· 2 shared Kamil Przytulski· 2 shared Kinga JurczakiD· 2 shared Marta KlejnotiD· 2 shared Michał WalczakiD· 2 shared Sylvain CottensiD· 2 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMolecular Biology

Anna SzlachcicORCID

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2 papers

Recent·Most cited

Molecular BiologyChemMedChemPeer-reviewedApr 3, 2026

Ligand-induced Conformational Plasticity of the CTLH E3 Ligase Receptor GID4

Daria Kotlarek, Katarzyna Dudek, Bartosz Woźniak…·Michał Walczak

This study designs high-affinity ligands for the E3 ligase GID4 to enable targeted protein degradation, identifying conformational changes and potential degrader structures, though degradation efficacy remains to be optimized.

DOI 10.1002/cmdc.202500849

experimental assaydrug response / drug discovery

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Molecular BiologyCommunications ChemistryPeer-reviewedAug 14, 2025

Targeted degradation of GSPT1 and NEK7 by a molecular glue prodrug for treatment of HCC

Przemysław Glaza, Roman Pluta, Krzysztofa E. Odrzywół…·Michał Walczak

The paper identifies ABS-752, a molecular glue prodrug that degrades GSPT1 and NEK7 in HCC cells, showing potent in vitro and in vivo activity.

7 citations

humanexperimental assay

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