Author

Kamil Przytulski

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:E. coli· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

Anna SzlachciciD· 3 shared Daria Gajewska· 3 shared Michał WalczakiD· 3 shared Aleksandra Podkowka· 2 shared Janusz WiśniewskiiD· 2 shared Kinga JurczakiD· 2 shared Magdalena Sypien· 2 shared Marta KlejnotiD· 2 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersMolecular Biology

Anna SzlachcicORCID

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3 papers

Recent·Most cited

Ligand-induced Conformational Plasticity of the CTLH E3 Ligase Receptor GID4

Daria Kotlarek, Katarzyna Dudek, Bartosz Woźniak, Martyna W. Pastok, Dmitrii V. Shishov, Sylvain Cottens, Michał Biśta, Emilia Krzywiecka, Karolina Maria Górecka, Kinga Jurczak, Tomáš Drmota, Justyna Adamczyk, Szymon Faliński, Daria Gajewska, Marta Klejnot, , Michał Walczak

This study designs high-affinity ligands for the E3 ligase GID4 to enable targeted protein degradation, identifying conformational changes and potential degrader structures, though degradation efficacy remains to be optimized.

ChemMedChem · Apr 3, 2026Peer-reviewedMolecular Biology

Targeted degradation of GSPT1 and NEK7 by a molecular glue prodrug for treatment of HCC

Przemysław Glaza, Roman Pluta, Krzysztofa E. Odrzywół, Marta Klejnot, Maria Wieczorek, Sylvain Cottens, Donald Coppen, Paweł Dobrzański, Tomáš Drmota, Joanna Lis-Grześniak, Agata Śnieżewska, Joanna Majkut, Martyna Mianowska, Paulina Rozborska, Marta Jarmuszkiewicz, , Michał Walczak

The paper identifies ABS-752, a molecular glue prodrug that degrades GSPT1 and NEK7 in HCC cells, showing potent in vitro and in vivo activity.

Communications Chemistry · Aug 14, 2025Peer-reviewedMolecular Biology

Expression screen of TNFR1 R347A, MyD88, IRAK4 death domains in E. coli followed by purification and biophysical characterization of TNFR1 R347A death domain

Kamil Przytulski, Aleksandra Podkowka, Tomasz Tomczyk, Daria Gajewska, Magdalena Sypien, Agnieszka Maria Jeleń, Priyanka Dahate, Anna Szlachcic, Michał Biśta, Michał Walczak

The paper optimizes expression and characterizes the stability of TNFR1 R347A, MyD88, and IRAK4 death domains in E. coli.

bioRxiv · Dec 13, 2024 · PreprintBiochemistry