Author

Lucy J. Minkley

Imperial College LondonORCID 0000-0002-3432-0032Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Organism:Drosophila· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

Alicia Estacio‐GómeziD· 1 shared Arjunan Rajasingam· 1 shared Claire S. DurrantiD· 1 shared Colin Derek McClureiD· 1 shared Freya StoreriD· 1 shared James H. CattersoniD· 1 shared Linda PartridgeiD· 1 shared Magda Luciana AtilanoiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMolecular Biology

Alicia Estacio‐GómezORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintApr 25, 2025

Sex-lethal is recruited to chromatin to promote neuronal tRNA synthesis in males through RNA Polymerase III regulation

Freya Storer, Colin Derek McClure, Alicia Estacio‐Gómez…·Tony D. Southall

This study identifies a splicing-independent role for Sxl in regulating RNA Polymerase III activity and tRNA synthesis in Drosophila neurons, impacting neuronal metabolism and ageing.

DOI 10.1101/2025.04.25.650657

DrosophilaChIP-seq

𝕏 PostBluesky

NeuroscienceNeurobiology of AgingPeer-reviewedSep 21, 2023

Aβ toxicity rescued by protein retention in the ER

James H. Catterson, Lucy J. Minkley, Salomé Aspe…·Linda Partridge

This study shows that retaining proteins in the ER can rescue Aβ toxicity in Drosophila and mouse models, suggesting a potential therapeutic strategy for Alzheimer's disease.

9 citations

Drosophilamouse

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