Magda Luciana Atilano

This study shows that redox imbalance in Drosophila models of Gaucher and Parkinson's disease leads to renal dysfunction, which contributes to systemic decline and neurodegeneration.

The paper identifies reduced PUFA levels in FTD/ALS models and shows neuronal PUFA supplementation improves survival and reduces neuronal death.

This study identifies Smpd1's role in tracheal gas-filling in Drosophila embryos by regulating ceramide-specific chitin-clearance, showing that lipid metabolism defects contribute to respiratory dysfunction.

This study shows that Gba1 deletion in flies causes immune hyperactivation and microbial dysbiosis, which can be mitigated by microbiome modulation or autophagy stimulation.

This study shows that retaining proteins in the ER can rescue Aβ toxicity in Drosophila and mouse models, suggesting a potential therapeutic strategy for Alzheimer's disease.

This study shows that increasing pyruvate import in neurons rescues dementia-like phenotypes in fly models by clearing toxic protein deposits.