Author

Riccardo Sirtori

University of Rhode IslandORCID 0000-0002-3454-4562Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Organism:mouse· 1

Frequent Co-Authors

Claudia FalliniiD· 3 shared Alicia Collins· 2 shared Michelle Gregoire· 2 shared Antonia RattiiD· 1 shared Bartosz WasickiiD· 1 shared Bhavya Chatragadda· 1 shared Burak ÖzkaniD· 1 shared Cedric Jan· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersNeuroscience

Claudia FalliniORCID

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3 papers

Recent·Most cited

Defective synapto-nuclear signaling contributes to motoneuron vulnerability in SOD1-ALS

Kamil Grycz, Cedric Jan, Piotr Zawistowski, Bartosz Wasicki, Burak Özkan, Oumayma Aousji, Riccardo Sirtori, Claudia Fallini, Guillaume Caron, Simon M. Danner, Francesco Roselli, Daniel Zytnicki, Marcin Bączyk

The paper investigates synapto-nuclear signaling defects in mSOD1 mice and shows that restoring cAMP/PKA signaling mitigates pathology in motoneurons.

bioRxiv · Sep 4, 2026 · PreprintNeuroscience

LINC complex alterations are a hallmark of sporadic and familial ALS/FTD

Riccardo Sirtori, Michelle Gregoire, Emily M. Potts, Alicia Collins, Liviana Donatelli, Claudia Fallini

This study identifies LINC complex alterations as a key feature in ALS/FTD, showing their presence in both genetic and sporadic cases and their correlation with nuclear morphology changes.

bioRxiv · Mar 8, 2024 · PreprintNeuroscience

Altered nuclear envelope homeostasis is a key pathogenic event in C9ORF72-linked ALS/FTD

Riccardo Sirtori, Michelle Gregoire, Alicia Collins, Serena Santangelo, Bhavya Chatragadda, Robert Cullen, Antonia Ratti, Claudia Fallini

This study identifies altered nuclear envelope homeostasis as a key pathogenic event in C9ORF72-linked ALS/FTD, showing that restoring NE tensional homeostasis can rescue NPC injury and reduce DNA damage.

bioRxiv · Feb 1, 2024 · PreprintNeuroscience