Author

Ozgur Sahin

Medical University of South Carolina

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cancer Biology· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Ariel MadrigaliD· 2 shared Fadi BrimoiD· 2 shared Hamed Shateri NajafabadiiD· 2 shared Minjun KimiD· 2 shared Morag ParkiD· 2 shared Mustafa SoytaşiD· 2 shared Özge SaatciiD· 2 shared Simon TanguayiD· 2 shared

Activity by Year

2018-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Ariel MadrigalORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Lysyl oxidase drives ccRCC progression by coordinating HIF-2α transcription program with tumor microenvironment

Bürge Ulukan, Özge Saatci, Ariel Madrigal, Minjun Kim, Wensheng Tian, Mustafa Soytaş, Zohreh Mehrjoo, Ozlem Sener Sahin, Kukkamadi Sreenivas, C.N.R. Rao, Tamiko Nishimura, Virginie Pillon, Jean-Sebastian Anoma, Elizabeth Hill, Janusz Rak, , Ozgur Sahin

This study identifies LOX as a driver of ccRCC progression by sustaining HIF-2α transcription and modulating the tumor microenvironment.

bioRxiv · Jul 27, 2026 · PreprintCancer Biology

Single-cell gene programs define subtype identity and metastatic trajectories in renal cell carcinoma

Ariel Madrigal, Minjun Kim, Zohreh Mehrjoo, Tamiko Nishimura, Özge Saatci, Adrien Osakwe, Evelyn Zavacky, Elham Moslemi, Kate I. Glennon, Matthew Dankner, Sarah M. Maritan, Hellen Kuasne, Virginie Pilon, Anie Monast, Mustafa Soytaş, , Hamed Shateri Najafabadi

This study identifies 59 gene expression programs in RCC that reveal subtype identity and metastatic trajectories, including a metastatic signature linked to poor clinical outcomes.

medRxiv · Jul 16, 2026 · PreprintGenetic & Genomic Medicine

Myosin filaments reversibly generate large forces in cells

James Lohner, Jean-Francois Rupprecht, Junquiang Hu, Nicola Mandriota, Mayur Saxena, James Hone, Diego Pitta de Araujo, Ozgur Sahin, Jacques Prost, Michael P. Sheetz

The paper challenges current understanding of molecular motor force generation by showing that myosin filaments generate large reversible forces in cells through collective behavior.

bioRxiv · Apr 9, 2018 · PreprintBiophysics