Loss of WNT2B Increases Progression from Dysplasia to Colorectal Cancer
Luiz Fernando Silva Oliveira, Yu-Syuan Wu, Sathuwarman Raveenthiraraj, Jaedeok Kwon, Venkata Siva Dasuri, Comfort Adegboye, Juan Putra, Jorge O. Múnera, Diana L. Carlone, David T. Breault, Amy E. O’Connell
This study shows that loss of WNT2B promotes colorectal cancer progression in mouse models and is associated with poor patient survival in human samples.
bioRxiv · Aug 21, 2025 · PreprintCancer Biology