Author

Shane Clerkin

F. Hoffmann-La Roche AGORCID 0000-0002-3493-0439Unclaimed ORCID profile · follow to get notified of new preprints

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1

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A. Rizkallah· 1 shared Alex OdermattiD· 1 shared Angélique Augustin· 1 shared Barbara HöllbacheriD· 1 shared Chiara Zanini· 1 shared Christelle Zundel· 1 shared Christine BeckeriD· 1 shared Claire Simonneau· 1 shared

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2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

A. Rizkallah

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1 paper

Recent·Most cited

Cell BiologyStem Cell ReportsPeer-reviewedAug 21, 2025

ApoE4 disrupts intracellular trafficking and iron homeostasis in an improved iPSC-based model of human brain endothelial cells

Luisa Bell, Shane Clerkin, Filiz Sila Rizalar…·Roberto Villaseñor

The paper investigates how ApoE4 affects intracellular trafficking and iron homeostasis in human brain endothelial cells derived from iPSCs, showing altered endosomal organization and iron levels.

6 citations

humanbulk RNA-seq

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