Author

Filiz Sila Rizalar

F. Hoffmann-La Roche AGORCID 0000-0002-9103-4681Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Cell Biology· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 3 Approach:experimental assay· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Angélique Augustin· 2 shared Roberto VillaseñoriD· 2 shared A. Rizkallah· 1 shared Alex OdermattiD· 1 shared Andreas Ritzau‐JostiD· 1 shared Barbara HöllbacheriD· 1 shared Chiara Zanini· 1 shared Christelle Zundel· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

Angélique Augustin

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Integrin-dependent trafficking of CD98hc reduces endocytic noise to maintain metabolic homeostasis

Filiz Sila Rizalar, Hans Peter Grimm, Angélique Augustin, Jose Luis Garcia-Cordero, Roberto Villaseñor

This study identifies a role for β1-integrin in regulating CD98hc trafficking to reduce endocytic noise and maintain amino acid homeostasis.

bioRxiv · Jul 27, 2026 · PreprintCell Biology

ApoE4 disrupts intracellular trafficking and iron homeostasis in an improved iPSC-based model of human brain endothelial cells

Luisa Bell, Shane Clerkin, Filiz Sila Rizalar, A. Rizkallah, Nadine Stokar‐Regenscheit, Xandor M. Spijkers, Nienke R. Wevers, Claire Simonneau, Angélique Augustin, Barbara Höllbacher, Lia D’Abate, Joanna Ficek, Kim Schneider, Désirée von Tell, Thomas L. Maurissen, , Roberto Villaseñor

The paper investigates how ApoE4 affects intracellular trafficking and iron homeostasis in human brain endothelial cells derived from iPSCs, showing altered endosomal organization and iron levels.

Stem Cell Reports · Aug 21, 2025Peer-reviewedCell Biology

NMDA-receptor-Fc-fusion constructs neutralize anti- NMDA receptor antibodies

Stephan Steinke, Toni Kirmann, Eleonora A Loi, Jana Nerlich, Iron Weichard, Philipp Kühn, Torsten Bullmann, Andreas Ritzau‐Jost, Filiz Sila Rizalar, Harald Prüß, Volker Haucke, Christian Geis, Michael Hust, Stefan Hallermann

This study develops NMDA-receptor-Fc-fusion constructs that neutralize anti-NMDA receptor antibodies and inhibit their effects on neurons.

Brain · Dec 28, 2022Peer-reviewedNeuroscience