Author

Dennis Huang

City University of New YorkORCID 0000-0002-3494-1656Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1

Frequent Co-Authors

Patrizia CasacciaiD· 3 shared Sarah MoyoniD· 2 shared Angeliki MelaiD· 1 shared Benjamin A. GarciaiD· 1 shared Boguslawa SadowskiiD· 1 shared David Anthony LyonsiD· 1 shared David K. DansuiD· 1 shared Katy LH Marshall-PhelpsiD· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersNeuroscience

Patrizia CasacciaORCID

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3 papers

Recent·Most cited

NeuroscienceNeoplasiaPeer-reviewedAug 30, 2024

PDGF-BB overexpression in p53 null oligodendrocyte progenitors increases H3K27me3 and induces transcriptional changes which favor proliferation

Dennis Huang, Angeliki Mela, Natarajan V. Bhanu…·Patrizia Casaccia

This study shows that PDGF-BB overexpression in p53 null OPCs increases H3K27me3 and promotes proliferation by altering transcription.

2 citations

mousebulk RNA-seq

𝕏 PostBluesky

NeurosciencebioRxivPreprintFeb 6, 2024

The epigenetic landscape of oligodendrocyte progenitors changes with time

David K. Dansu, Sami Sauma, Dennis Huang…·Patrizia Casaccia

The study identifies histone modifications H4K8ac and H4K20me3 that regulate transcriptional differences between adult and neonatal oligodendrocyte progenitors.

5 citations

𝕏 PostBluesky

NeurosciencebioRxivPreprintMar 6, 2020

TET1-mediated DNA hydroxy-methylation regulates adult remyelination

Sarah Moyon, Rebecca Frawley, Katy LH Marshall-Phelps…·Patrizia Casaccia

This study shows that TET1-mediated DNA hydroxy-methylation is essential for adult remyelination, with loss of function leading to impaired myelin repair in aged mice.

9 citations

𝕏 PostBluesky