Author
Washington University in St. LouisORCID 0000-0002-2552-0489Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Fenjie Li, Xingui Wu, Yixuan Xie, Jiafeng Yang, Jiaojiao Xi, Yuetong Sun, Jiazhang Chen, Xiao Guang Wu, Shenwei Huang, Chi Zhang, Yi Zheng, Wenwen Li, Xiaoyu Zuo, Li Yang, Kaining Chen, , Yan Zhang
The paper identifies nuclear N-glycosylation as a novel modification that influences cell identity and is linked to neurodevelopmental disorders.
bioRxiv · Dec 19, 2025 · PreprintCell Biology
Xiaoqing Cheng, Jacob Hsia, Jesus Iraheta, Joanna M. Gongora, Maureen K. Highkin, Xiaohua Jin, Zhanfang Guo, Julie L. Prior, John R. Edwards, Shunqiang Li, Ian S. Hagemann, Cynthia X. Ma, Zongtao Lin, Benjamin A. Garcia, Ron Bose
This study shows that HER2 and TP53 co-mutant cancers have increased histone acetylation and are sensitive to neratinib plus trastuzumab deruxtecan.
bioRxiv · Jul 6, 2025 · PreprintCancer Biology
Hanbyeol Kim, Do‐Gyun Kim, Seongyun Ha, Jun-Young Jang, Francisca N. de Luna Vitorino, Joanna M. Gongora, Woochul Kim, Yoonji Oh, Gyeongsik Park, Hyeji Kang, Soo-Hyun Im, Chan Kwon Jung, Seon-Young Kim, Inkyung Jung, Jae‐Kyung Won, , Chul‐Hwan Lee
This study shows that the EZH1Q571R mutation enhances chromatin compaction and PRC2 activity, leading to repression of tumor suppressor genes in follicular thyroid cancer.
bioRxiv · May 6, 2025 · PreprintMolecular Biology
Dennis Huang, Angeliki Mela, Natarajan V. Bhanu, Benjamin A. Garcia, Peter Canoll, Patrizia Casaccia
This study shows that PDGF-BB overexpression in p53 null OPCs increases H3K27me3 and promotes proliferation by altering transcription.
Neoplasia · Aug 30, 2024Peer-reviewedNeuroscience