Subhanita Ghosh

This study identifies glucocorticoid signalling as a barrier to dendritic cell immunotherapy in glioblastoma and shows that targeting NR3C1 can restore DC function and enhance anti-tumor responses.

This paper demonstrates CRISPR/Cas9-mediated gene editing in the nematode Nippostrongylus brasiliensis using extracellular vesicles to deliver Cas9/guide RNA complexes, achieving targeted gene disruption.

The paper identifies mutations in E3 ubiquitin ligases that restore development in SWI/SNF mutants in C. elegans, suggesting potential therapeutic targets for human developmental disorders.

The paper shows piRNAs are expressed in somatic muscles of Manduca sexta and regulate transposons during muscle atrophy and programmed cell death.

The paper shows that the Integrator complex cleaves nascent piRNA precursors to terminate promoter-proximal Pol II transcription in C. elegans.