So Gun Hong

This study explores using cMPL as a target to selectively deplete human hematopoietic stem cells, showing potential for safer pre-transplant conditioning.

The paper demonstrates a method to track ex vivo generated B cells in non-human primates using PET imaging, showing stable distribution and feasibility of repeated infusions.

This study investigates how clonal hematopoiesis affects COVID-19 severity and pathophysiology in rhesus macaques, finding prolonged inflammation and higher viral persistence in CH animals.

The paper validates off-target effects of CRISPR/Cas9 in rhesus macaques using error-corrected sequencing, showing that in vitro and in silico methods have limited predictive accuracy.

This paper reports a case of clonal hematopoiesis in a rhesus macaque following lentiviral transduction of HSPC with a strong retroviral promoter, leading to gene overexpression and aberrant splicing.