Author

Heiko Düßmann

Royal College of Surgeons in IrelandORCID 0000-0002-3582-8057Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Jochen H.M. PrehniD· 3 shared Batuhan KısakoliD· 2 shared John Patrick BurkeiD· 2 shared Alessandro MichelucciiD· 1 shared Anaïs OudiniD· 1 shared Anna GolebiewskaiD· 1 shared Anna SturrockiD· 1 shared Arman Raman· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersCancer Biology

Jochen H.M. PrehnORCID

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3 papers

Recent·Most cited

Cell engulfment defines spatially distinct competitive metabolic niches associated with clinical outcomes in colorectal cancer

Emir Bozkurt, Batuhan Kısakol, Heiko Düßmann, Federico Lucantoni, Anna Sturrock, Mohammadreza Azimi, Sanghee Cho, Elizabeth McDonough, Joana Fay, Tony O’Grady, John P. Burke, Niamh McCawley, Deborah A. McNamara, Daniel B. Longley, Fiona Ginty, Jochen H.M. Prehn

The paper investigates cell engulfment in colorectal cancer, showing it creates competitive metabolic niches linked to clinical outcomes.

Cell Death and Differentiation · Jun 30, 2026Peer-reviewedCancer Biology

A multi-step filtering pipeline for human read removal enhances detection of Fusobacterium in WGS datasets with immunohistochemical confirmation in mucinous rectal cancer.

Mariia S. Frolova, Barry Maguire, Heiko Düßmann, Menatallah Rayan, Caoimbhe Burke, Hesham Mohamed Korashy, Arman Raman, William M. Gallagher, John Patrick Burke, Simon J. Furney, Jochen H.M. Prehn

The paper introduces a multi-step filtering pipeline to remove human reads from WGS data, improving detection of Fusobacterium in rectal cancer samples confirmed by immunohistochemistry.

bioRxiv · Nov 24, 2025 · PreprintBioinformatics

Humanized glioblastoma patient-derived orthotopic xenografts recreate a locally immunosuppressed human immune ecosystem amenable to immunotherapeutic modulation

Pilar M. Moreno‐Sanchez, Anaïs Oudin, Batuhan Kısakol, Heiko Düßmann, Eliane Klein, Virginie Baus, Camille Rolin, Carole Seguin‐Devaux, Mahsa Rezaeipour, Aurélie Poli, Alessandro Michelucci, Jérôme Paggetti, Etienne Moussay, Jochen H.M. Prehn, Simone P. Niclou, Anna Golebiewska

This study develops humanized glioblastoma PDOX models to study tumor-immune interactions and test immunotherapies in a human context.

bioRxiv · Nov 20, 2025 · PreprintCancer Biology