Michael Hothorn

Catalase import into peroxisomes in Arabidopsis

This study identifies a minimal C-terminal targeting motif for plant catalases that enables their peroxisomal import in Arabidopsis.

A mechanistic framework for the recognition of chemically diverse brassinosteroids by BRI1-family receptor kinases

The paper quantifies BR receptor binding kinetics and identifies key chemical features for receptor recognition, revealing structural plasticity and functional diversity in BR signaling.

Plant Kelch phosphatases are Ser/Thr phosphatases involved in cell cycle regulation

This study reclassifies plant Kelch phosphatases as PP1-like serine/threonine phosphatases involved in cell cycle regulation rather than tyrosine phosphatases in brassinosteroid signaling.

Structure of the Arabidopsis receptor kinase SRF6 ectodomain determined from crystals obtained using the LRR crystallisation screen

The paper reports the crystal structure of the SRF6 ectodomain from Arabidopsis, obtained using a novel LRR crystallization screen, revealing structural features and potential signaling roles outside the brassinosteroid pathway.

An inositol pyrophosphate interaction screen provides insight into the regulation of plant casein kinase II

The paper identifies PP-InsP-interacting complexes in Arabidopsis, including CK2 subunits, and shows InsP6 modulates CK2 activity by blocking substrate binding.

A small signaling domain controls PPIP5K phosphatase activity in phosphate homeostasis.

This study identifies a GAF signaling domain that regulates PPIP5K phosphatase activity in phosphate homeostasis through structural and functional analyses.

Inositol pyrophosphate catabolism by three families of phosphatases controls plant growth and development

This study identifies three phosphatase families involved in inositol pyrophosphate catabolism in plants, showing their roles in growth, development, and nutrient signaling.