Author

Ellen R. Langille

Mount Sinai HospitalORCID 0000-0002-3616-3616Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Christian A. Lee· 1 shared Daniel SchramekiD· 1 shared Diala Abd-RabboiD· 1 shared Elisa PasiniiD· 1 shared Evgenija Serafimova· 1 shared Huayun HouiD· 1 shared Jüri ReimandiD· 1 shared Kevin C.L. ChengiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Christian A. Lee

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1 paper

Recent·Most cited

Cancer BiologyNature CommunicationsPeer-reviewedNov 21, 2025

Topoisomerase IIb binding underlies frequently mutated elements in cancer genomes

Liis Uusküla-Reimand, Christian A. Lee, Robin Hyunseo Oh…·Jüri Reimand

The paper identifies TOP2B binding sites as mutational hotspots in cancer genomes, showing their role in structural variants and driver mutations in genes like TP53 and MYC.

6 citations

humanwhole-genome sequencing

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