Author

Vignesh Vudatha

Virginia Commonwealth UniversityORCID 0000-0002-3624-3771Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Organism:human· 1 Organism:mouse· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Jose TrevinoiD· 2 shared Andrés Gutiérrez-GarcíaiD· 1 shared António M. PalmaiD· 1 shared Daohong ZhouiD· 1 shared Eduardo MorenoiD· 1 shared Esha MadaniD· 1 shared Eyal DavidiD· 1 shared Guangrong ZhengiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCancer Biology

Jose TrevinoORCID

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2 papers

Recent·Most cited

The combination of BCL-xL PROTAC and mTOR inhibitor sensitizes pancreatic ductal adenocarcinoma to KRASG12D inhibitor treatment by enhancing apoptosis induction

Javed Miyan, Vignesh Vudatha, Lin Cao, Peiyi Zhang, Guangrong Zheng, Lei Zheng, Jose Trevino, Daohong Zhou, Sajid Khan

This paper shows that combining BCL-xL PROTAC and mTOR inhibitor with KRASG12D inhibitor enhances apoptosis and overcomes resistance in PDAC.

bioRxiv · Jan 5, 2026 · PreprintCancer Biology

Neighbor-specific gene expression revealed from physically interacting cells during mouse embryonic development

Junil Kim, Michaela Rothová, Esha Madan, Siyeon Rhee, Guangzheng Weng, António M. Palma, Linbu Liao, Eyal David, Ido Amit, Morteza Chalabi Hajkarim, Vignesh Vudatha, Andrés Gutiérrez-García, Eduardo Moreno, Robert A. Winn, Jose Trevino, , Kyoung‐Jae Won

The paper introduces PIC-seq to study cell-cell contact-specific gene expression during mouse embryonic development and identifies novel gene expression signatures dependent on neighboring cell types.

Proceedings of the National Academy of Sciences · Jan 3, 2023Peer-reviewedDevelopmental Biology