Author

Sajid Khan

The University of Texas at San Antonio Health Science Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Organism:human· 2 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

Daohong ZhouiD· 2 shared Angel A. Dominguez· 1 shared Chenhui He· 1 shared Francis E. SharkeyiD· 1 shared Guangrong ZhengiD· 1 shared Han XuiD· 1 shared Javed Miyan· 1 shared Jose TrevinoiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

Daohong ZhouORCID

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2 papers

Recent·Most cited

The combination of BCL-xL PROTAC and mTOR inhibitor sensitizes pancreatic ductal adenocarcinoma to KRASG12D inhibitor treatment by enhancing apoptosis induction

Javed Miyan, Vignesh Vudatha, Lin Cao, Peiyi Zhang, Guangrong Zheng, Lei Zheng, Jose Trevino, Daohong Zhou, Sajid Khan

This paper shows that combining BCL-xL PROTAC and mTOR inhibitor with KRASG12D inhibitor enhances apoptosis and overcomes resistance in PDAC.

bioRxiv · Jan 5, 2026 · PreprintCancer Biology

NF2 loss malignantly transforms human pancreatic acinar cells and enhances cell fitness under environmental stress

Yi Xu, Michael H Nipper, Angel A. Dominguez, Chenhui He, Francis E. Sharkey, Sajid Khan, Han Xu, Daohong Zhou, Lei Zheng, Yu Luan, Jun Liu, Pei Wang

This study identifies NF2 as a critical tumor suppressor in PDAC, showing its role in promoting invasive behavior, enhancing cell fitness under stress, and contributing to drug resistance.

Journal of Clinical Investigation · Jan 1, 2026Peer-reviewedCancer Biology