Eduardo Moreno

The paper identifies a bilateral communication module involving Fwe, Grindelwald/TNFR, and Veli/LIN-7 that mediates cell competition in Drosophila.

This study identifies Hbs and Rst adhesion molecules as regulators of cell elimination during epithelial remodelling in Drosophila, showing they define a regional code for cell removal.

This paper describes an ex-vivo protocol for extended live imaging of adult Drosophila brains to study cell competition over 32 hours.

This study shows that dietary interventions affect cell competition and locomotion in a Drosophila Alzheimer's model, with synthetic diets delaying disease progression.

This study examines Azot expression dynamics after traumatic brain injury in Drosophila, showing increased apoptotic elimination of 'loser' cells and expanded cell competition to include both neurons and glia.

This study characterizes heterotypic competition between cancer cells and hepatocytes, showing varying competitiveness and its impact on metastatic phenotypes.

This study identifies Ikebana as a modulator of Flower-dependent cell competition, showing its role in regulating loser cell elimination in various contexts.

This study examines the dynamics of Flower-dependent cell competition markers in Drosophila over 28 days, revealing that Azot is not required for loser cell elimination and that most apoptotic cells express both Fwe LB and Azot.

The paper introduces PIC-seq to study cell-cell contact-specific gene expression during mouse embryonic development and identifies novel gene expression signatures dependent on neighboring cell types.

The paper shows that tissue compaction induces cell elimination via ERK downregulation and Hid upregulation, contributing to clone expansion and tumor progression in Drosophila.

The paper shows that removing less fit neurons in a Drosophila AD model reduces amyloid-β42-induced brain damage and cognitive/motor decline.

This study shows that the Toll pathway inhibits tissue growth and enhances cell fitness in an infection-dependent manner by regulating apoptosis and proliferation.

The paper shows that Myc-induced cell mixing through intercalation drives competitive tissue invasion and destruction by altering cell interface tension and promoting loser cell elimination.