Iván Soler

Distinct changes to hippocampal and medial entorhinal circuits emerge across the progression of cognitive deficits in epilepsy

This study examines how hippocampal and medial entorhinal circuit dysfunction evolves with cognitive deficits in epilepsy using in vivo electrophysiology in mice.

The longitudinal behavioral effects of acute exposure to galactic cosmic radiation in female C57BL/6J mice: implications for deep space missions, female crews, and potential antioxidant countermeasures

This study examines the long-term behavioral effects of galactic cosmic radiation on female mice and evaluates the protective effects of an antioxidant compound.

Progressive excitability changes in the medial entorhinal cortex in the 3xTg mouse model of Alzheimer's disease pathology

The paper examines excitability changes in the medial entorhinal cortex of 3xTg mice at early and late stages of Alzheimer's disease pathology, finding hyperexcitability in specific cell types and altered synaptic ratios.

Chronotate: An open-source tool for manual timestamping and quantification of animal behavior

Chronotate is an open-source tool for manually scoring rodent behavior videos, providing detailed temporal data to analyze interaction patterns in novel object tasks.

Multi-domain cognitive assessment of male mice reveals whole body exposure to space radiation is not detrimental to high-level cognition and actually improves pattern separation.

The paper exposes male mice to space radiation and finds no detrimental effect on high-level cognition, with improved pattern separation performance.