Zoé Christenson Wick

This study identifies KMT2E as a reader of H3K4me3Q5ser, showing its role in regulating chromatin dynamics and neurodevelopmental gene expression in ODLURO syndrome.

The paper examines neural activity in the medial entorhinal cortex and hippocampus of 3xTg mice, finding that reduced theta power and coherence, along with disrupted phase locking, coincide with the onset of spatial memory impairment in a model of Alzheimer's disease.

This study demonstrates that inhibitory theta phase locking in interneurons directly controls seizure susceptibility using a closed-loop optogenetic system.

This study examines how hippocampal and medial entorhinal circuit dysfunction evolves with cognitive deficits in epilepsy using in vivo electrophysiology in mice.

The paper investigates how stress-induced plasticity in the amygdala and ventral hippocampus differentially supports non-associative defensive behaviors.

The paper examines excitability changes in the medial entorhinal cortex of 3xTg mice at early and late stages of Alzheimer's disease pathology, finding hyperexcitability in specific cell types and altered synaptic ratios.

Chronotate is an open-source tool for manually scoring rodent behavior videos, providing detailed temporal data to analyze interaction patterns in novel object tasks.

This study shows that strong aversive experiences in mice drive offline reactivation of both recent aversive and older neutral memories, linking them across days.

This study shows that selectively knocking out the GABAAα1 subunit in Purkinje cells induces a tremor phenotype, similar to Essential Tremor, without affecting survival or motor function.

The paper identifies a novel hippocampal neuronal population, LINCs, which are GABAergic interneurons with long-range axons, influencing hippocampal and extrahippocampal network function.