Şefayet Karaca

Shared epigenetic regulation acting on neuroimmune pathways contributes to the comorbidity between generalized anxiety disorder and COVID-19

The paper identifies shared epigenetic and genetic loci between generalized anxiety disorder and COVID-19, implicating neuroimmune pathways in their comorbidity.

Multivariate genome-wide association study dissects shared biology and disorder-specific loci across internalizing spectrum in millions of ancestrally diverse participants

This study identifies shared and disorder-specific genetic loci across internalizing disorders using a multivariate genome-wide association approach in diverse populations.

Multivariate genome-wide association study of suicidal behaviors in >1.7 million individuals of diverse population descents

This paper identifies 90 genome-wide significant SNPs for suicidal behaviors in diverse populations, with 49 novel findings, and highlights genetic correlations with mental and physical health traits.

Multi-ancestry genome-wide association study of endometriosis and its clinical manifestations in ~1.4 million women: translating gene discovery into pathogenic mechanisms and therapeutic targets

This study identifies 80 genome-wide significant associations for endometriosis and adenomyosis in 1.4 million women, uncovering novel loci and pathways involved in disease mechanisms.