Yaira Z. Nuñez

This study conducts a multi-ancestry GWAS meta-analysis of 2.5 million participants to identify genetic variants associated with migraine and link them to biological pathways and therapeutic targets.

The paper identifies shared epigenetic and genetic loci between generalized anxiety disorder and COVID-19, implicating neuroimmune pathways in their comorbidity.

This study identifies 49 CpG sites associated with generalized anxiety disorder across three ancestries but finds limited replication in an independent cohort.

This study identifies 1,257 genetic variants associated with human personality traits using large-scale GWAS and finds widespread genetic correlations with behaviors and life outcomes.

This study performs a multi-ancestral GWAS of DSM-defined nicotine dependence, finding genetic correlations with other substance use disorders and health traits, and identifying a strong general addiction liability factor.

This study identifies 178 independent risk loci for depression through a large meta-analysis across multiple cohorts, including fine-mapping and transcriptome-wide association findings.

This study identifies epigenomic changes in African American Transthyretin Val122Ile carriers linked to heart disease and outpatient surgeries, revealing dysregulated amyloid mechanisms.

The paper investigates gene-environment interactions between polysubstance dependence and suicidal behaviors using two cohorts, finding significant associations and gene clusters linked to these interactions.