Author

Henning Hvid

Novo Nordisk (Denmark)ORCID 0000-0002-3667-4141Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:spatial transcriptomics· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Assay:scRNA-seq· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1

Frequent Co-Authors

Charles PykeiD· 3 shared Simon J. Baumgart· 2 shared Vivek DasiD· 2 shared Alban Laus Obel Slabowska· 1 shared Anne BableriD· 1 shared Brian LamiD· 1 shared Georgina K.C. DowsettiD· 1 shared Giles S.H. YeoiD· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersBioinformatics

Charles PykeORCID

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Author profile →

3 papers

Recent·Most cited

A Benchmark of state-of-the-art Deconvolution Methods in Spatial Transcriptomics: Insights from Cardiovascular Disease and Chronic Kidney Disease

Alban Laus Obel Slabowska, Charles Pyke, Henning Hvid, Leon Eyrich Jessen, Simon J. Baumgart, Vivek Das

This study benchmarks three deconvolution methods in spatial transcriptomics for cardiovascular and kidney diseases, finding comparable performance with method-specific trade-offs.

Frontiers in Bioinformatics · Mar 27, 2024Peer-reviewedBioinformatics

Encompassing view of spatial and single-cell RNA-seq renews the role of the microvasculature in human atherosclerosis

Tore Bleckwehl, Sidrah Maryam, Anne Babler, Michael Nyberg, Markus Høybye Bosteen, Maurice Halder, Charles Pyke, Henning Hvid, Louise Marie Voetmann, Judith C. Sluimer, Vivek Das, Simon J. Baumgart, Rafael Kramann, Sikander Hayat

The paper integrates single-cell RNA-seq and spatial transcriptomics data to reveal cellular interactions and changes in human atherosclerosis.

bioRxiv · Dec 15, 2023 · PreprintBioinformatics

Human HYPOMAP: A comprehensive spatio-cellular map of the human hypothalamus

John A. Tadross, Lukas Steuernagel, Georgina K.C. Dowsett, Katherine A. Kentistou, Sofia Hult Lundh, Marta Porniece, Paul Klemm, Kara Rainbow, Henning Hvid, Katarzyna Kania, Joseph Polex-Wolf, Lotte Bjerre Knudsen, Charles Pyke, John R. B. Perry, Brian Lam, , Giles S.H. Yeo

The paper presents HYPOMAP, a comprehensive spatio-cellular map of the human hypothalamus, identifying BMI-associated genes and potential druggable targets.

bioRxiv · Sep 15, 2023 · PreprintNeuroscience