Christopher Schmied

This study identifies septin-associated PIPKIγ splice variants as essential for midbody organization by generating PI(4,5)P2 required for centralspindlin recruitment and septin-microtubule association.

The paper presents a morphological profiling dataset of EU-OPENSCREEN bioactive compounds across multiple imaging sites and cell lines, validated for robustness and used to map profiles to activity and toxicity.

This paper introduces a semi-supervised contrastive learning method for bioactivity prediction from Cell Painting image data, improving classification of pharmacological classifications and biological targets.

LO_SCPLOWABKITC_SCPLOW is a Fiji plugin for efficient segmentation of big image data, supporting manual and automated routines on single- and multi-channel images and timelapse movies.

The paper shows that enriched environment increases inter-individual variability in brain and behavior traits in mice.