Viktoria Haghani

This study shows that ZC4H2 loss of function in human neural stem cells and organoids leads to premature neuronal differentiation and impaired neurogenesis, with potential therapeutic restoration through a codon-optimized transgene.

Rocketchip improves rigor and reproducibility in ChIP-seq, CUT&RUN, and CUT&Tag data analysis by enabling comparison and swapping of analysis components.

This study investigates the effects of excess prenatal folic acid on mouse brain transcriptome and methylome, revealing altered gene expression and electrophysiological changes.

The paper identifies sex-specific transcriptomic changes in a mouse model of Rett syndrome, showing more differentially expressed genes in females and non-cell-autonomous effects.

The paper integrates CTCF loops, methylome, and transcriptome data from LUHMES neurons to study imprinting dynamics at the 15q11-q13 locus during differentiation.

The paper identifies and validates enhancers active in early postnatal mouse brain using a modified MPRA approach and rAAV delivery.