Osman Sharifi

Female cortical cellular mosaicism underlies shared MeCP2 and PCB impacted gene pathways

The paper investigates how PCB exposure interacts with MeCP2 mutations in female mice, identifying shared gene pathways and transcriptional impacts in the cortex.

Improving rigor and reproducibility in chromatin immunoprecipitation assay data analysis workflows with Rocketchip

Rocketchip improves rigor and reproducibility in ChIP-seq, CUT&RUN, and CUT&Tag data analysis by enabling comparison and swapping of analysis components.

Light and sex modify Snord116 genotype effects on metabolism, behavior, and imprinted gene networks following circadian entrainment

The paper examines how Snord116 genotype interacts with light and sex to influence metabolism, behavior, and imprinted gene networks in mice after circadian entrainment.

Sex-specific single cell-level transcriptomic signatures of Rett syndrome disease progression

The paper identifies sex-specific transcriptomic changes in a mouse model of Rett syndrome, showing more differentially expressed genes in females and non-cell-autonomous effects.

Integration of CTCF Loops, Methylome, and Transcriptome in Differentiating LUHMES as a Model for Imprinting Dynamics of the 15q11-q13 Locus in Human Neurons

The paper integrates CTCF loops, methylome, and transcriptome data from LUHMES neurons to study imprinting dynamics at the 15q11-q13 locus during differentiation.