Macrophages tune responses to pathogen dynamics through TLR4 stimulation memory and by licensing susceptibility to IL-10
Hannes Bongartz, Christopher T. Boughter, Bernadette Marrero, Thorsten Prüstel, Clinton J. Bradfield, Julia L. Gross, Rachel A. Gottschalk, Aleksandra Nita‐Lazar, Iain D. C. Fraser, Martin Meier‐Schellersheim
The paper shows macrophages use TLR4 memory and IL-10 susceptibility gating to adjust inflammation based on pathogen dynamics.
bioRxiv · Mar 28, 2024 · PreprintImmunology