Luye An

Rebuilding the autoimmune-damaged corneal stroma through topical lubrication

This study shows that topical lubrication can regenerate the damaged corneal stroma in a mouse model by converting inflammatory keratocytes into reparative cells.

Rescue of non-healing, degenerative salivary glands by cholinergic-calcium signaling

This study shows that muscarinic agonists can restore non-healing salivary glands by reactivating endogenous regeneration and mitochondrial function through cholinergic-calcium signaling.

A stable mode of bookmarking by TBP recruits RNA Polymerase II to mitotic chromosomes

The paper shows TBP remains bound to promoters during mitosis, stabilizing RNA Polymerase II association and enabling transcriptional reactivation.

A Dynamic Mode of Mitotic Bookmarking by Transcription Factors

The paper shows that many transcription factors remain bound to mitotic chromosomes, challenging previous findings of their exclusion and revealing dynamic interactions that depend on DNA binding and nuclear import.