Author

Jacob J. Zulk

Baylor College of MedicineORCID 0000-0002-3758-5503Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

Kathryn A. PatrasiD· 4 shared Addison B. Larson· 3 shared Camille Serchejian· 3 shared Samantha OttingeriD· 3 shared Zainab A. HameediD· 3 shared Allyson E. SheaiD· 2 shared Anthony William MaressoiD· 2 shared Clare M. RobertsoniD· 2 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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Curved chords = mutual co-authorship

4 shared papersMicrobiology

Kathryn A. PatrasORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Distinct maternofetal immune signatures delineate preterm birth onset following urinary tract infection

Samantha Ottinger, Addison B. Larson, Vicki Mercado-Evans, Holly Branthoover, Jacob J. Zulk, Camille Serchejian, Libbie Ogilvie, Marlyd E. Mejia, Zainab A. Hameed, Ryan Walde, Rachel C. Fleck, Christopher Scott Ward, Allyson E. Shea, Kathryn A. Patras

This study identifies immune signatures in mice and human urine that predict preterm birth risk following UTI, highlighting cytokines like IL-10 and IL-15 as potential therapeutic targets.

Science Translational Medicine · Aug 26, 2026Peer-reviewedImmunology

Type 2 diabetes mellitus exacerbates vaginal group B Streptococcus colonization via impaired mucosal cytokine response

Clare M. Robertson, Vicki Mercado-Evans, Addison B. Larson, Holly Branthoover, Samantha Ottinger, Marlyd E. Mejia, Zainab A. Hameed, Lindsey A. Gonzalez, Camille Serchejian, Libbie Ogilvie, Jacob J. Zulk, Kathryn A. Patras

This study shows that type 2 diabetes increases susceptibility to vaginal group B Streptococcus colonization through impaired cytokine responses, not via glucose availability or microbiome changes.

mSphere · Jul 10, 2026Peer-reviewedMicrobiology

Bacteriophage-mediated reduction of uropathogenic E. coli from the urogenital epithelium

Bishnu Joshi, Jacob J. Zulk, Camille Serchejian, Zainab A. Hameed, Addison B. Larson, Austen Lee Terwilliger, Deepak Kumar, Indira U. Mysorekar, Robert A. Britton, Anthony William Maresso, Kathryn A. Patras

This study shows that bacteriophages can reduce uropathogenic E. coli (UPEC) colonization in vitro and in a mouse model, suggesting phage therapy as a potential UTI prevention strategy.

Infection and Immunity · Feb 26, 2026Peer-reviewedMicrobiology

Human bladder organoids model urinary tract infection and bacteriophage therapy

Jacob J. Zulk, Clare M. Robertson, Samantha Ottinger, Amal Kambal, Alejandra Rivera Tostado, Rachel C. Fleck, Allyson E. Shea, Cristian Coarfa, Sarah Elizabeth Blutt, Anthony William Maresso, Kathryn A. Patras

This study develops human bladder organoids to model UTIs and phage therapy, showing phage reduces bacterial loads and inflammation during infection.

bioRxiv · Jul 30, 2025 · PreprintMicrobiology