Author

Aurélien Laguerre

Oregon Health & Science UniversityORCID 0000-0002-3765-3254Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1 Research Focus:protein design· 1 Assay:proteomics· 1

Frequent Co-Authors

Carsten SchultziD· 3 shared Alix Thomas· 1 shared Braden T. LobingieriD· 1 shared David K. GrandyiD· 1 shared Dmytro A. YushchenkoiD· 1 shared Frank SteiniD· 1 shared Jian QiuiD· 1 shared Jona RadaiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersNeuroscience

Carsten SchultzORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Identifying Novel Estrogenic Mitochondrial Targets in Hypothalamic Proopiomelanocortin Neurons by Chemoproteomics

Jian Qiu, Martha A. Bosch, Mya S. Wolfe, Ksenija Korać, Stefano Rizzo, Todd L. Stincic, Scotland E. Farley, Wendy Fitzgerald, Megha Rajendran, Aurélien Laguerre, Frank Stein, Philip F. Copenhaver, Oline K. Rønnekleiv, Sean M. Ronnekleiv‐Kelly, Tatiana K. Rostovtseva, , Martin J. Kelly

This study identifies STX, a non-steroidal estrogenic compound, as targeting mitochondrial VDAC2 to enhance bioenergetics and provide neuroprotection in hypothalamic POMC neurons.

bioRxiv · Aug 21, 2026 · PreprintNeuroscience

Cannabinoid Receptor Signaling is Dependent on Sub-Cellular Location

Alix Thomas, Braden T. Lobingier, Carsten Schultz, Aurélien Laguerre

This study shows that cannabinoid receptor 1 (CB1) signaling depends on its subcellular location, which is controlled by promoters and N-terminal tags, and demonstrates a method to tag receptors without disrupting signaling.

bioRxiv · Mar 21, 2024 · PreprintMolecular Biology

Trace Amines are Essential Metabolites for the Autocrine Regulation of β-Cell Signaling and Insulin Secretion

Sebastian Hauke, Kaya Keutler, Aurélien Laguerre, Mireia A. Carbo, Jona Rada, David K. Grandy, Dmytro A. Yushchenko, Carsten Schultz

This study identifies trace amines (TAs) as essential autocrine signaling factors for β-cell activity and insulin secretion, showing their modulation affects intracellular Ca2+ oscillations and insulin release.

bioRxiv · Mar 21, 2024 · PreprintBiochemistry