Braden T. Lobingier

This study identifies the Retromer complex as a key mediator of MOR recycling via the LENL motif, preventing opioid-induced downregulation.

This study identifies how DNAJC13's endosomal localization is regulated by its J domain and C-terminal tail through interactions with PI(3)P and oligomerization.

This study shows that cannabinoid receptor 1 (CB1) signaling depends on its subcellular location, which is controlled by promoters and N-terminal tags, and demonstrates a method to tag receptors without disrupting signaling.

The paper identifies novel regulators of mu opioid receptor signaling and trafficking using proximity labeling and proteomics.

This study develops a biosensor to map opioid receptor activation in neurons, showing drugs activate receptors in the Golgi and dendrites, while peptides activate them in the plasma membrane and endosomes.