Carsten Schultz

This study identifies STX, a non-steroidal estrogenic compound, as targeting mitochondrial VDAC2 to enhance bioenergetics and provide neuroprotection in hypothalamic POMC neurons.

This paper describes a protocol for profiling lipid-protein interactions using multifunctional lipid probes and provides methods for conjugate preparation and proteomic analysis.

The paper investigates how cells process multiple environmental signals using imaging and RNAseq, revealing nonlinear interactions and vulnerabilities in cancer cells.

This study shows that glucagon and GLP-1 promote pseudo-islet formation and influence islet fragmentation differently in male and female donors.

This paper introduces a genetically encoded FRET probe (pARS) for real-time monitoring of PARylation dynamics in vitro and in live cells, showing its utility in detecting PARP1 activity and inhibitor potency.

This study shows that cannabinoid receptor 1 (CB1) signaling depends on its subcellular location, which is controlled by promoters and N-terminal tags, and demonstrates a method to tag receptors without disrupting signaling.

This study identifies trace amines (TAs) as essential autocrine signaling factors for β-cell activity and insulin secretion, showing their modulation affects intracellular Ca2+ oscillations and insulin release.

The paper synthesizes three palmitic acid derivatives with diazirine at different positions and shows that end-position diazirines crosslink distinct protein subsets.

This paper introduces GECCO, a thermogenetic system for manipulating calcium levels in cells and tissues, enabling studies of calcium signaling in plants and animals.

The paper shows that posttranscriptional regulation, specifically translational repression, controls the onset of differentiation in adult neural stem cells.

The paper investigates how combinatorial extracellular cues influence intracellular signaling network activity and cellular responses in human cells.