Author

J. Marie Hardwick

Johns Hopkins UniversityORCID 0000-0002-4847-2045Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:whole-genome sequencing· 2 Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Organism:fungi (other)· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Arturo CasadevalliD· 3 shared Madhura KulkarniiD· 3 shared Ao Shen· 2 shared Quigly DragotakesiD· 2 shared Amanda DziedziciD· 1 shared Anne JedlickaiD· 1 shared Bingnan Jin· 1 shared Chengzhang ZhuiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersMicrobiology

Arturo CasadevallORCID

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3 papers

Recent·Most cited

The heat-ramp method to study regulated cell death in a pathogenic yeastCryptococcus neoformans

Madhura Kulkarni, Yining Liu, Quanxi Cheng, Chengzhang Zhu, Kuhn Ke, Ao Shen, Bingnan Jin, Arturo Casadevall, Heather M. Lamb, Zachary D. Stolp, J. Marie Hardwick

The paper introduces a heat-ramp method to study regulated cell death in Cryptococcus neoformans, revealing a protracted cell death process in pathogenic yeast.

Methods in cell biology · Jan 1, 2026Peer-reviewedMicrobiology

A method for authenticating the fidelity of Cryptococcus neoformans knockout collections

Ella Jacobs, Quigly Dragotakes, Madhura Kulkarni, Kimberly Kuhn, Ao Shen, Amanda Dziedzic, Anne Jedlicka, J. Marie Hardwick, Arturo Casadevall

The paper identifies mixed plates in a Cryptococcus neoformans knockout collection and proposes an authentication method to distinguish between different KO libraries.

Microbiology Spectrum · Aug 28, 2025Peer-reviewedMicrobiology

Human and murine Cryptococcus neoformans infection selects for common genomic changes in an environmental isolate.

Poppy Sephton-Clark, Scott A. McConnell, Nina T. Grossman, Rosanna P. Baker, Quigly Dragotakes, Yunfan Fan, Man Shun Fu, Gracen R. Gerbig, Seth D. Greengo, J. Marie Hardwick, Madhura Kulkarni, Stuart M. Levitz, Joshua Daniel Nosanchuk, Shmuel Shoham, Daniel F. Q. Smith, , Arturo Casadevall

The paper shows that environmental Cryptococcus neoformans strains undergo genomic and phenotypic changes during mammalian infection, suggesting animal virulence drives genetic adaptation.

bioRxiv · Apr 12, 2022 · PreprintGenomics