Commonalities and differences in the Cryptococcus neoformans response to ingestion by protozoal and mammalian phagocytic cells suggests host cell metabolism as a target for intracellular survival
Quigly Dragotakes, Ella Jacobs, Gracen R. Gerbig, Seth D. Greengo, Anne Jedlicka, Amanda Dziedzic, Arturo Casadevall
This study isolates and characterizes cryptococcal phagosomes from different host cells, revealing conserved fungal responses and suggesting host metabolism as a target for survival.
PLoS Pathogens · Dec 26, 2025Peer-reviewedMicrobiology