Author

João Almeida‐Coelho

Universidade do PortoORCID 0000-0002-3769-8962Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Agata BakiD· 1 shared Alejandro Clemente-MantecaiD· 1 shared Andra C. DumitruiD· 1 shared Carlos Pérez‐MedinaiD· 1 shared David Sánchez-OrtiziD· 1 shared Diana Velázquez-CarrerasiD· 1 shared Elías Herrero‐GalániD· 1 shared Enrique CalvoiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiophysics

Agata BakORCID

Mutual co-authors in cluster

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1 paper

Recent·Most cited

Pathological stiffening by crosslinking glycation of titin

Agata Bak, Andra C. Dumitru, Alejandro Clemente-Manteca, Enrique Calvo, Roberto Silva‐Rojas, Natalia Vicente, David Sánchez-Ortiz, Inés Martínez-Martín, Diana Velázquez-Carreras, María Rosaria Pricolo, Francisco M. Espinosa, João Almeida‐Coelho, Carlos Pérez‐Medina, Ricardo Alexandrino Garcia, Jesús Vázquez, , Jorge Alegre‐Cebollada

This study shows that glycation of cardiac titin increases in diabetes, leading to protein and cardiomyocyte stiffening through crosslinking advanced glycation end products.

bioRxiv · Feb 14, 2026 · PreprintBiophysics