Author

Ricardo Alexandrino Garcia

Consejo Superior de Investigaciones CientíficasORCID 0000-0002-7115-1928Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Ricardo Alexandrino Garcia1 paper · Bristol-Myers Squibb (United States)

Biology Disciplines

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Biophysics· 1 Developmental Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Organism:zebrafish· 1

Frequent Co-Authors

Agata BakiD· 1 shared Alejandro Clemente-MantecaiD· 1 shared Álvaro González-RajaliD· 1 shared Andra C. DumitruiD· 1 shared Andrés González-GuerraiD· 1 shared Carlos Pérez‐MedinaiD· 1 shared Carlos R. GuerreroiD· 1 shared Cristina Márquez-López· 1 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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Focal author (center)Selected co-authorORCID co-authorUnlinked name

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1 shared paperBiophysics

Agata BakORCID

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Author profile →

3 papers

Recent·Most cited

Pathological stiffening by crosslinking glycation of titin

Agata Bak, Andra C. Dumitru, Alejandro Clemente-Manteca, Enrique Calvo, Roberto Silva‐Rojas, Natalia Vicente, David Sánchez-Ortiz, Inés Martínez-Martín, Diana Velázquez-Carreras, María Rosaria Pricolo, Francisco M. Espinosa, João Almeida‐Coelho, Carlos Pérez‐Medina, Ricardo Alexandrino Garcia, Jesús Vázquez, , Jorge Alegre‐Cebollada

This study shows that glycation of cardiac titin increases in diabetes, leading to protein and cardiomyocyte stiffening through crosslinking advanced glycation end products.

bioRxiv · Feb 14, 2026 · PreprintBiophysics

SARS-CoV-2 protein Nsp1 alters actomyosin cytoskeleton and phenocopies arrhythmogenic cardiomyopathy-related PKP2 mutant

Cristina Márquez-López, Marta Roche-Molina, Nieves García-Quintáns, Silvia Sacristán, David Siniscalco, Andrés González-Guerra, Emilio Camafeita, Mariya Lytvyn, María I. Guillen, David Sanz‐Rosa, Daniel Martín-Pérez, Cristina Sánchez‐Ramos, Ricardo Alexandrino Garcia, Juan Antonio Bernal

The paper shows that SARS-CoV-2 Nsp1 protein mimics the effects of a PKP2 mutant by altering actomyosin cytoskeleton organization, suggesting a potential link between viral infection and ACM-like disease.

bioRxiv · Sep 14, 2020 · PreprintMolecular Biology

Loss of Caveolin-1 and caveolae leads to increased cardiac cell stiffness and functional decline of the adult zebrafish heart

Dimitrios Grivas, Álvaro González-Rajal, Carlos R. Guerrero, Ricardo Alexandrino Garcia, José Luís de la Pompa

This study shows that loss of Caveolin-1 in zebrafish leads to increased cardiac cell stiffness and impaired heart function, but allows for heart regeneration after injury.

Scientific Reports · Jul 30, 2020Peer-reviewedDevelopmental Biology