Author
Spanish National Centre for Cardiovascular ResearchORCID 0000-0001-5712-0984Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Laura Sen-Martín, Ángel Fernández‐Trasancos, Miguel Ángel López-Unzu…·Jorge Alegre‐Cebollada
This study shows that myosin inhibition with mavacamten is effective in treating HCM caused by both truncating and missense variants in MYBPC3, despite different pathomechanisms.
Agata Bak, Andra C. Dumitru, Alejandro Clemente-Manteca…·Jorge Alegre‐Cebollada
This study shows that glycation of cardiac titin increases in diabetes, leading to protein and cardiomyocyte stiffening through crosslinking advanced glycation end products.
Christopher T. A. Lewis, Roger Moreno‐Justicia, Lola Savoure…·Julien Ochala
This study investigates altered myosin super-relaxation and energy metabolism in type II diabetes using muscle biopsies and proteomic analyses, finding increased super-relaxation and reduced ATP demand.