Jay Patel

The paper introduces a dataset of VHH-Fc antibodies and shows that IgG-trained models outperform VHH-Fc-specific models in predicting developability properties.

This paper redirects cytomegalovirus (CMV)-specific T cells to target pancreatic cancer, showing improved tumor control and survival in mice.

This study shows that inhibiting MIF reduces mechanical hyperalgesia in CisIPN without affecting CP's anti-tumor effects.

The paper introduces a high-throughput platform to generate large datasets for training machine learning models to predict antibody developability properties.

This study identifies Neurog2 as a potential therapeutic target for MYCN-driven neuroendocrine prostate cancer by showing its role in promoting tumor growth and NEPC development.

This study identifies MICAL2 as a super enhancer-associated gene that promotes pancreatic cancer growth and metastasis through multiple molecular mechanisms.

This study shows that combining SUMO inhibition with CD40 agonism enhances anti-tumor immunogenicity in PDAC by improving macrophage function and T-cell infiltration, leading to improved survival in a mouse model.