Author

James Lee

UC San Diego Health SystemORCID 0000-0003-3079-5484Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Alexei MartsinkovskiyiD· 1 shared Alfredo MolinoloiD· 1 shared Andrew M. LowyiD· 1 shared Antonia D. BoyeriD· 1 shared Asimina S. CourelliiD· 1 shared Christine LawsoniD· 1 shared Colin C. AndersoniD· 1 shared Cray Minor· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCancer Biology

Alexei MartsinkovskiyORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintSep 12, 2025

Ovarian Tumor FAK Inhibition Releases Omega-3 Fatty Acids Stimulating GATA6 Peritoneal Macrophage CXCL13 Production Enhancing Immunotherapy

Xiao Lei Chen, Kevin M. Tharp, Marjaana Ojalill…·David D. Schlaepfer

This study shows FAK inhibition in ovarian tumors increases macrophage CXCL13 production via omega-3 fatty acids, enhancing B cell infiltration and immunotherapy response.

DOI 10.1101/2025.09.12.675975

mousehuman

𝕏 PostBluesky

Cancer BiologybioRxivPreprintDec 3, 2024

SUMO Inhibition Plus CD40 Agonism Increases Anti-Tumor Immunogenicity Through Interferon Mediated Macrophage Activation

Kevin Li, Asimina S. Courelli, James Lee…·Andrew M. Lowy

This study shows that combining SUMO inhibition with CD40 agonism enhances anti-tumor immunogenicity in PDAC by improving macrophage function and T-cell infiltration, leading to improved survival in a mouse model.

1 citation

mouseexperimental assay

𝕏 PostBluesky