Alessandro Pini

This study uses molecular dynamics simulations to show that branching in SET-M33 reduces self-aggregation while maintaining membrane association compared to its linear counterpart Q33.

This paper introduces a conditional variational autoencoder for antimicrobial peptide generation, combining QSAR data and cross-entropy optimization to overcome limitations in generative models.

This study evaluates the efficacy of the synthetic antimicrobial peptide SET-M33 against poultry pathogens, showing broad inhibition of bacterial growth and host compatibility in intestinal organoids.

This study evaluates the antimicrobial peptide SET-M33 against Glaesserella parasuis and porcine commensals, showing its selectivity and potential for in vitro use.

This paper introduces a compact prism-based microscope for sensitive detection of biomarkers in fluid samples, achieving a 1 fg/mL limit of detection for bacterial lipopolysaccharides.

This paper introduces two branched oncolytic peptides, BOP7 and BOP9, which target HSPGs, inhibit metastasis, and induce immunogenic cell death in pancreatic cancer cells.