The paper presents a single-nucleus RNA sequencing atlas of Aedes aegypti mosquitoes, identifying novel cell types and sexual dimorphism in gene expression across tissues.

Cell · Oct 30, 2025Peer-reviewedGenomics

Arboviruses disrupt salivary gland organization and decrease salivation in Aedes aegypti mosquitoes

Lucie Souriac, Mateus Antonio Berni, Benjamin Voisin, Carlos F. Estevez-Castro, Marine Le Berder, Roenick Proveti Olmo, Thiago H. J. F. Leite, Hacène Medkour, Julien Pompon, Éric Marois, Fabien Aubry, João Trindade Marques

This study shows that arboviruses reduce salivation in Aedes aegypti mosquitoes by disrupting salivary gland organization, potentially enhancing virus transmission.

bioRxiv · May 16, 2025 · PreprintImmunology

A population modification gene drive targeting both Saglin and Lipophorin impairs Plasmodium transmission in Anopheles mosquitoes

Emily I Green, Etienne Jaouen, Dennis Klug, Roenick Proveti Olmo, Amandine Gautier, Stéphanie A. Blandin, Éric Marois

This paper describes a gene drive targeting Saglin and Lipophorin in Anopheles mosquitoes to reduce Plasmodium transmission, showing successful spread in caged populations.

eLife · Dec 5, 2023Peer-reviewedGenetics

Genomic Analysis of Two Phlebotomine Sand Fly Vectors of Leishmania from the New and Old World

Frédéric Labbé, Maha Abdeladhim, Jenica Abrudan, Alejandra Saori Araki, Ricardo N. Araújo, Peter Arensburger, Joshua B. Benoit, Reginaldo Peçanha Brazil, Rafaela Vieira Bruno, Gustavo Bueno da Silva Rivas, Vinicius Carvalho de Abreu, Jason Charamis, Iliano V. Coutinho-Abreu, Samara Costa, Alistair C. Darby, , Mary Ann McDowell

The paper sequences and annotates the genomes of two sand fly species, identifying genes related to vector biology and population structure to aid in leishmaniasis control.

bioRxiv · Oct 5, 2022 · PreprintGenomics