Author

Zewen Jiang

Nurix (United States)ORCID 0000-0002-3852-8666Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Immunology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Aileen KellyiD· 1 shared Aishwarya KumariD· 1 shared Alexis J. CombesiD· 1 shared Arthur Sands· 1 shared Arum YooiD· 1 shared Atefeh RabieeiD· 1 shared Austin Tenn-McClellaniD· 1 shared Brandon J. Bravo· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperCancer Biology

Aileen KellyORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Bexobrutideg: A Selective, Catalytic Degrader of Bruton's Tyrosine Kinase Overcomes Inhibitor Resistance and Suppresses Autoantibody-Mediated Disease

Mark Noviski, P Auger, Danielle Bautista, Nivetha Brathaban, Brandon J. Bravo, Robert Cass, Ganesh Cherala, Thomas C. Fung, Stefan Gajewski, Dhwani Haria, Zewen Jiang, Dane E. Karr, Aileen Kelly, Daisuke Kato, Zef A. Könst, , Frederick Cohen

Bexobrutideg is a BTK degrader that overcomes inhibitor resistance and suppresses autoimmune disease by catalytically degrading BTK.

bioRxiv · Aug 4, 2026 · PreprintCancer Biology

Transient Dietary Changes Modulate Inflammatory Disease Trajectory in the Lean State

Zewen Jiang, John M. Tayeri, Chihiro Tabuchi, Sarah G. Gayer, Arum Yoo, Im‐Hong Sun, Jiaxi Wang, Han Yin, Shin Shyan Chuah, Preetal Deshpande, Vrinda Johri, Brittany R. Davidson, Jessica L. Tsui, Nicholas F. Kuhn, Tristan Courau, , Sagar P. Bapat

This study shows that a short-term high-fat diet during the onset of psoriasis worsens disease severity through immune system changes, even after returning to a normal diet.

bioRxiv · Jun 15, 2025 · PreprintImmunology

A CRISPR-based genome-wide screen for adipogenesis reveals new insights into mitotic expansion and lipogenesis.

Rachel E. Turn, Keren I. Hilgendorf, Carl T. Johnson, Kyuho Han, Atefeh Rabiee, János Demeter, Mohammad Ovais Aziz‐Zanjani, Pablo Domizi, Ran Cheng, Yingdi Zhu, Zewen Jiang, Katrin J. Svensson, Michael Cory Bassik, Peter K. Jackson

The paper uses a CRISPR-based screen in 3T3-L1 cells to identify regulators of adipogenesis, finding that protein translation and stability mechanisms are critical for adipocyte expansion and lipogenesis.

bioRxiv · Jul 13, 2020 · PreprintMolecular Biology