Author

Guillermo Martinez Corrales

IBMB-CSICORCID 0000-0002-3923-5902Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:Drosophila· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Adrian M. IsaacsiD· 1 shared Alec J. VincentiD· 1 shared Alexander J. HulliD· 1 shared Benjamin Aleyakpo· 1 shared Carlo Sala FrigerioiD· 1 shared David Osumi-SutherlandiD· 1 shared Dongwei XuiD· 1 shared Dunxin SheniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Adrian M. IsaacsORCID

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2 papers

Recent·Most cited

A transient pulse of neuronal ATF4 installs a durable non-autonomous programme promoting healthy ageing

Paula Suarez Distasio, Oscar Tovar Ferrero, Sasha Saint-Roman, Oliver Mitev, Marc Liesa Roig, Guillermo Martinez Corrales

This study shows that transient ATF4 activation in neurons during early adulthood extends healthspan and promotes systemic adaptations in Drosophila.

bioRxiv · Nov 4, 2026 · PreprintPhysiology

Differential neuronal vulnerability to C9orf72 repeat expansion driven by Xbp1 transcription signature

Dunxin Shen, Alec J. Vincent, Evan Udine, Yazead Buhidma, Sharifah Anoar, Elli Tsintzas, Marie Emilie Maeland, Dongwei Xu, Mireia Carcolé, David Osumi-Sutherland, Benjamin Aleyakpo, Alexander J. Hull, Guillermo Martínez-Corrales, Nathaniel S. Woodling, Rosa Rademakers, , Teresa Niccoli

The paper identifies neuronal vulnerability to C9orf72 repeat expansion by analyzing transcriptional states in a Drosophila model, finding that Xbp1 expression correlates with resistance to toxicity.

Cell Reports · Apr 1, 2025Peer-reviewedNeuroscience