Author

Elli Tsintzas

University College London

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Organism:Drosophila· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Adrian M. IsaacsiD· 2 shared Alec J. VincentiD· 2 shared Benjamin Aleyakpo· 2 shared Dongwei XuiD· 2 shared Dunxin SheniD· 2 shared Marie Emilie MaelandiD· 2 shared Sharifah AnoariD· 2 shared Teresa NiccoliiD· 2 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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2 shared papersNeuroscience

Adrian M. IsaacsORCID

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2 papers

Recent·Most cited

Differential neuronal vulnerability to C9orf72 repeat expansion driven by Xbp1 transcription signature

Dunxin Shen, Alec J. Vincent, Evan Udine, Yazead Buhidma, Sharifah Anoar, Elli Tsintzas, Marie Emilie Maeland, Dongwei Xu, Mireia Carcolé, David Osumi-Sutherland, Benjamin Aleyakpo, Alexander J. Hull, Guillermo Martínez-Corrales, Nathaniel S. Woodling, Rosa Rademakers, , Teresa Niccoli

The paper identifies neuronal vulnerability to C9orf72 repeat expansion by analyzing transcriptional states in a Drosophila model, finding that Xbp1 expression correlates with resistance to toxicity.

Cell Reports · Apr 1, 2025Peer-reviewedNeuroscience

A monocarboxylate transporter rescues frontotemporal dementia and Alzheimer's disease models

Dongwei Xu, Alec J. Vincent, Andrés González‐Gutiérrez, Benjamin Aleyakpo, Sharifah Anoar, Ashling Giblin, Magda Luciana Atilano, Mirjam Lisette Adams, Dunxin Shen, Annora Thoeng, Elli Tsintzas, Marie Emilie Maeland, Adrian M. Isaacs, Jimena A. Sierralta, Teresa Niccoli

This study shows that increasing pyruvate import in neurons rescues dementia-like phenotypes in fly models by clearing toxic protein deposits.

PLoS Genetics · Sep 21, 2023Peer-reviewedNeuroscience