Joan T. Matamalas

Nanoparticle-enabled plasma proteomics of a mouse atherosclerosis model

This study uses nanoparticle-enhanced plasma proteomics to identify low-abundant proteins in atherosclerosis-prone mice, revealing disease-related changes in inflammation, lipid metabolism, and potential biomarkers.

Cross-species proteomics quantification pipeline distinguishes donor versus host extracellular matrix in explanted biomaterials

The paper develops a cross-species proteomics pipeline to distinguish donor and host ECM proteins in explanted biomaterials, showing that single-species analysis leads to inaccurate quantification.

Integrating pharmacogenomics and cheminformatics with diverse disease phenotypes for cell type-guided drug discovery

This paper introduces Pathopticon, a network-based method integrating pharmacogenomics, cheminformatics, and disease phenotypes to prioritize cell lines and drugs for cell type-guided drug discovery.