Author

Francis Bitsch

Novartis Institutes for BioMedical ResearchORCID 0000-0002-3929-702XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein design· 1 Assay:protein sequence· 1 Assay:proteomics· 1

Frequent Co-Authors

Anne‐Christine UldryiD· 1 shared Christelle Gasser-Didierlaurant· 1 shared Christian N. ParkeriD· 1 shared Frederic D. SigoillotiD· 1 shared Isabel SchmidtiD· 1 shared Jana ZiegelmülleriD· 1 shared Julian Schoenbett· 1 shared Jürgen ReinhardtiD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Anne‐Christine UldryORCID

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1 paper

Recent·Most cited

Drug-induced eRF1 degradation promotes readthrough and reveals a new branch of ribosome quality control

Lukas‐Adrian Gurzeler, Marion Link, Yvonne Ibig, Isabel Schmidt, Olaf Galuba, Julian Schoenbett, Christelle Gasser-Didierlaurant, Christian N. Parker, Xiaohong Mao, Francis Bitsch, Markus Schirle, Philippe Couttet, Frederic D. Sigoillot, Jana Ziegelmüller, Anne‐Christine Uldry, , Jürgen Reinhardt

The paper introduces two novel readthrough promoters that induce eRF1 degradation, leading to PTC suppression and revealing a new ribosome quality control mechanism.

Cell Reports · Aug 30, 2023Peer-reviewedMolecular Biology