Author
Novartis Institutes for BioMedical ResearchORCID 0009-0003-7029-4489Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
3 papers
Recent·Most cited
Lukas‐Adrian Gurzeler, Marion Link, Yvonne Ibig…·Jürgen Reinhardt
The paper introduces two novel readthrough promoters that induce eRF1 degradation, leading to PTC suppression and revealing a new ribosome quality control mechanism.
Thomas Welte, Alison Goulois, Michael Beda Stadler…·Helge Großhans
The paper identifies TRIM71's mechanism of mRNA silencing through recruitment of TNRC6/GW182 and shows competition among silencing pathways.
Merve Mutlu, Isabel Schmidt, Andrew I. Morrison…·Danilo Guerini
This paper identifies AK59 as a molecular glue degrader for STING, showing HERC4 is the key E3 ligase for its degradation and demonstrating efficacy against STING mutations.